梅田までどうやって行くん?
Alisa and Mika are talking about how they get to Umeda from their respective parents' house.
Hints:
梅田(うめだ) = Umeda, a neighborhood in Osaka
実家(じっか) = parent's house
垂水(たるみ) = Tarumi, a neighborhood Kobe
JR(ジェイアール) = the Japanese national rail
東岸和田(ひだしきしわだ) = Higashikishiwada, an area south of Osaka